Assistant Professor
Areas of Interest: Cardiac remodeling, developmental biology
Office:WEGPHR 336
Phone:(585) 385-7209
Janet Lighthouse

Apple Teacher


Post-Doctoral Fellowship, University of Rochester Medical Center
Post-Doctoral Fellowship, Yale University
Ph.D., State University of New York at Stony Brook
M.S., Johns Hopkins University
B.S., Johns Hopkins University


  • PHAR 3240 – Biosystems I
  • PHAR 3244 – Systems Pharmacology II
  • PHAR 4144 – Systems Pharmacology III


Dr. Lighthouse received her Ph.D. from Stony Brook University in 2010 in molecular and cellular biology where she focused on early mammalian development. After graduation, she did her post-doctoral training, first at Yale University investigating the origin of vascular smooth muscle cells in pulmonary hypertension, and then at the University of Rochester Medical Center investigating transcriptional differences in cardiac fibroblasts between exercise and disease. She joined the faculty of the Wegmans School of Pharmacy as a full-time assistant professor in January 2020. Her primary research interests include cardiac remodeling and developmental biology.

Publications on Google Scholar

Professional Organizations

  • Society for Developmental Biology
  • American Heart Association
  • International Society for Heart Research

Selected Recent Publications

  • p53 Regulates the Extent of Fibroblast Proliferation and Fibrosis in Left Ventricle Pressure Overload. doi: 10.1161/CIRCRESAHA.121.320324. Circ Res. 2023 Jul 21. Co-authored with Xiaoyi Liu, Ryan M Burke, Cameron D Baker, Ronald A Dirkx Jr, Brian Kang, Yashoswini Chakraborty, Deanne M Mickelsen, Jennifer J Twardowski, Stephano S Mello, John M Ashton, Eric M Small.

  • Cell-Based Phenotypic Screen for Antifibrotic Compounds Targets Eicosanoid Metabolism. doi: 10.1161/CIRCRESAHA.122.322272. Circ Res. 2023 Jan 6. Co-authored with Eric M Small.

  • Prevention of Fibrosis and Pathological Cardiac Remodeling by Salinomycin. doi: 10.1161/CIRCRESAHA.120.317791. Circ Res. 2021 May 28. Co-authored with Ryan M. Burke, Ronald A. Dirkx Jr, Pearl Quijada, Amy Mohan, Meghann O’Brien, Wojciech Wojciechowski, Collynn F. Woeller, Richard P. Phipps, Jeffrey D. Alexis, John M. Ashton, Eric M. Small