Apple Teacher
Education:Post-Doctoral Fellowship: Center for Neurologic Diseases, Brigham and Women’s Hospital and Harvard Medical School, Boston
MA Ph.D. in Genetics, Stony Brook University, Stony Brook, NY
B.S. in Molecular Biology and Russian, Vanderbilt University, Nashville, TN
Dr. Wines-Samuelson has been a Visiting Assistant Professor in the Department of Pharmaceutical Sciences since August 2025. She has a Bachelor of Science from Vanderbilt University and a Ph.D. in Genetics from Stony Brook University. While pursuing her doctoral degree, she received the Sigma Xi Excellence in Research Award for her work on physical and transcript mapping that led to identification of a gene essential for embryonic development and mesoderm induction. Her postdoctoral research in the Center for Neurologic Diseases at Brigham and Women’s Hospital and Harvard Medical School in Boston identified roles for the Alzheimer’s disease causative gene Presenilin-1 in both brain development and in protection from synaptic loss and apoptosis in the adult brain, and was awarded an NIH training grant in Neurodegeneration. Following her postdoc, Dr. Wines-Samuelson joined the University of Rochester Medical Center (URMC) as a Research Assistant Professor in the Department of Biomedical Genetics, where she investigated how maternal gestational iron deficiency causes permanent effects on the brain via altered interneuron development and increased susceptibility to seizures. As a staff scientist at URMC in the Cardiovascular Research Institute, she used mouse genetic and surgical models of vascular disease to observe changes in endothelial cell translation efficiency under conditions of reduced blood flow. Altered ribosome function and translation lead to hyperproliferation, vascular inflammation, and loss of vessel elasticity. Prior to joining the Wegmans School of Pharmacy, Dr. Wines-Samuelson led a project in the Department of Endocrinology and Metabolism at URMC to determine the role of neutrophil extracellular traps (NETs) in a mouse model of uterine cancer with relevance to a human cystic lung disease, lymphangioleiomyomatosis (LAM).
Teaching
Dr. Wines-Samuelson is involved in co-teaching the following courses for the Campus Pathway and Online Pathway at the Wegmans School of Pharmacy:
- PHAR 3148 (OP) – Biosystems I (Fall) PHAR 3144 (CP) – Systems Pharmacology I (Fall)
- PHAR 3240 (OP/CP)- Biosystems II (Spring)
- PHAR 4244 (OP/CP)- Pharmacology IV (Spring)
Prior to joining Fisher, Dr. Wines-Samuelson taught courses in Molecular Biology, Cell Biology, General Biology, Animal Behavior, Developmental Neurobiology, Cardiovascular Biology, and Systems Biology.
Research
Her primary area of research interest is in the connection between neural development and neurodegeneration, and how abnormal development can lead to neuronal dysfunction and disease in the mature brain.
Publications